Biochemical aids in the diagnosis of Parkinson's disease.

Effect of ellagic acid on thiol levels in different brain tissue in an animal model of Parkinson's disease

Background & Aim: Parkinson's disease (PD) can be created with loss of dopaminergic substantial nigra neurons which is widely associated with oxidative stress and reduced glutathione (GSH), as the most important and abundant thiol in tissues and one of the antioxidant defense, is one of the earliest biochemical events related to Parkinson's and consumption of antioxidants has a protective effec...

Effect of ellagic acid on thiol levels in different brain tissue in an animal model of Parkinson's disease

Background & Aim: Parkinson's disease (PD) can be created with loss of dopaminergic substantial nigra neurons which is widely associated with oxidative stress and reduced glutathione (GSH), as the most important and abundant thiol in tissues and one of the antioxidant defense, is one of the earliest biochemical events related to Parkinson's and consumption of antioxidants has a protective effec...

The biochemical diagnosis of Wilson's disease in Iran

Diagnosis of patients with Parkinson's disease using quantitative susceptibility mapping

Introduction: Parkinson'sdisease isassociated withirondeposition in the brain. The T2-weighted imaging, T2* mapping, R2 mapping and Quantitative Susceptibility Mapping (QSM) are three common methods to evaluating the iron deposition in brain. Among three methods the QSM is more sensitive than others. Few studies have been used QSM for evaluating the iron deposition in the basa...

Investigating effect of chamomile hydroalcoholic extract on movement disorders in the animal model of Parkinson's disease

Background & Aim:Parkinson's disease (PD) is a kind of disorder in the nervous system, which is characterized with multiple movement disorders. Factors such as oxidative stress are the most important causes for the degeneration of dopaminergic neurons in the substantia nigra and occurrence of Parkinson's disease. Thus, medications that have antioxidant functions could be an int...

Strength-endurance training with olive oil consumption on motor performance and oxidative stress level in the brain of male parkinsonian rats.

Introduction: Parkinson's disease is a chronic brain disorder that occurs as a result of the loss, reduction or damage of dopamine-producing nerve cells in the substantia nigra located in the midbrain. The purpose of this study is to determine the effect of 8 weeks of strength-endurance training with olive oil consumption on motor performance and oxidative stress level in the brain of male park...